The instant invention discloses compositions and methods related to epsin
3, a novel protein closely related to, but distinct from previously
described epsins. Epsin 3 mRNA and protein are undetectable in
keratinocytes isolated from unwounded skin, but is induced in cells
following contact with fibrillar type I collagen. It is envisioned that
this protein plays an important role in activated epithelial cells during
tissue morphogenesis.