The present invention relates to 4-aryl triazoles having the formula:
##STR1##
wherein R.sup.1 is independently selected from the group consisting of:
lower alkyl, lower alkenyl, lower alkynyl, lower heteroalkyl, lower
heteroalkenyl, lower heteroalkynyl, heterocycloalkyl, heteroaryl, halo,
CN, OR.sup.4, SR.sup.4, S(O)R.sup.4, S(O).sub.2 R.sup.4, and NR.sup.4
R.sup.5 ; and Q is has the general formula:
##STR2##
said compounds are useful in treating diseases associated with unwanted
cytokine activity, inter alia, interleukin-1 (IL-1) and tumor necrosis
factor (TNF) from cells.
