Composition for treatment of constipation and irritable bowel syndrome

   
   

Constipation and Irritable Bowel Syndrome are treated by a delayed and sustained release composition of an opioid antagonist which commences release of the opioid antagonist in the mid to distal small intestine or ascending colon and provides sustained release along any remaining part of the small intestine and along the colon. Preferred opioid antagonists are naloxone and naltrexone.

O constipation e o syndrome irritable do bowel são tratados por uma composição atrasada e sustentada da liberação de um antagonista do opioid que comece a liberação do antagonista do opioid no mid ao intestine pequeno distal ou aos dois pontos ascending e forneça a liberação sustentada ao longo de qualquer peça restante do intestine pequeno e ao longo dos dois pontos. Os antagonistas preferidos do opioid são naloxone e naltrexone.

 
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