There are disclosed a method to enhance sternal treatment after sternotomy
with or without removal of at least one of thoracic arteries which
comprises applying an agent for the treatment of sternum after sternotomy
to or at around the sternum, wherein the agent comprises at least one
selected from the group consisting of an angiogenetic factor, an
osteogenetic factor and their analogues such as bFGF, aFGF, TGF .beta.,
VEGF, HGF, BMP, PDGF, TGF .alpha., other cytokines or gene as an effective
ingredient and an agent to be used for the method; and an agent to enhance
healing of or treating sternum after sternotomy comprising the same.
