The present invention provides antimicrobial sulfonamide derivatives of
lipopeptide antibiotics, pharmaceutical compositions of antimicrobial
sulfonamide derivatives, methods for making antimicrobial sulfonamide
derivatives, methods for inhibiting microbial growth with antimicrobial
sulfonamide derivatives and methods for treating or preventing microbial
infections in a subject with antimicrobial sulfonamide derivatives.
Antimicrobial sulfonamide derivatives are generally an amino core
antibiotic that has been further modified with a lipophilic sulfonyl
group.
