Kappa agonist compounds and pharmaceutical formulations thereof

   
   

Compounds having kappa opioid agonist activity, compositions containing them and method of using them as analgesics are provided. The compounds of formula IIIB have the structure: ##STR1## wherein R.sub.1, R.sub.2, R, Ar and n are as described in the specification.

De samenstellingen die kappa opioid agonist activiteit, samenstellingen hebben die hen en methode om hen als pijnstillende middelen bevat worden te gebruiken verstrekt. De samenstellingen van formule IIIB hebben de structuur: ## STR1 ## waarin R.sub.1, R.sub.2, R, AR en n zijn zoals die in de specificatie wordt beschreven.

 
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