Adjuvant compositions for modulating an immune response to an antigen
administered to a host comprise a mineral salt adjuvant and at least one
other adjuvant. The compositions provide an adjuvanting effect on an
antigen which is greater than the adjuvanting effect attainable by one of
the adjuvants alone. An antigen is covalently bonded to a glycolipid
analog to provide a discrete molecule which exhibits an enhanced
adjuvanting effect on the antigen which is greater than the adjuvanting
effect attainable in the absence of such covalent bonding.
