Receptor that binds trail

   
   

A protein designated TRAIL receptor binds the protein known as TNF-Related Apoptosis-Inducing Ligand (TRAIL). The TRAIL receptor finds use in purifying TRAIL or inhibiting activities thereof. Isolated DNA sequences encoding TRAIL-R polypeptides are provided, along with expression vectors containing the DNA sequences, and host cells transformed with such recombinant expression vectors. Antibodies that are immunoreactive with TRAIL-R are also provided.

Uma proteína designada receptor da FUGA liga a proteína sabida como Ligand deIndução TNF-Relacionado (FUGA). O uso dos achados do receptor da FUGA na FUGA purifying ou em atividades inibindo disso. As seqüências isoladas do DNA que codificam polypeptides de TRAIL-R são fornecidas, junto com os vetores da expressão que contêm as seqüências do DNA, e as pilhas de anfitrião transformadas com tais vetores recombinant da expressão. Os antibodies que são immunoreactive com TRAIL-R são fornecidos também.

 
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