Glucagon-like insulinotropic peptide analogs, compositions, and methods of use

   
   

Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives are disclosed. The analogs include amino acid substitutions, amino and carboxyl terminal modifications, and C.sub.6 -C.sub.10 acylations. The claimed compounds stimulate the secretion or biosynthesis of insulin in poorly functioning beta cells and are therefore useful in treating Type II diabetics

Glucagon-als insulinotropic peptide (glp-1(7-37 analogons)) en derivaten worden onthuld. De analogons omvatten aminozuursubstituties, amino en carboxyl eindwijzigingen, en C.sub.6 - acylations C.sub.10. De geëiste samenstellingen bevorderen de afscheiding of de biosynthese van insuline in slecht functionerende bètacellen en zijn daarom nuttig in het behandelen van Type II diabetici

 
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< In vivo production and delivery of erythropoietin for gene therapy

> Method of producing clonal cell strains which express exogenous DNA encoding glucagon-like peptide 1

> Insulinotropic hormone GLP-1 (7-36) and uses thereof

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