Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives
are disclosed. The analogs include amino acid substitutions, amino and
carboxyl terminal modifications, and C.sub.6 -C.sub.10 acylations. The
claimed compounds stimulate the secretion or biosynthesis of insulin in
poorly functioning beta cells and are therefore useful in treating Type II
diabetics
Glucagon-als insulinotropic peptide (glp-1(7-37 analogons)) en derivaten worden onthuld. De analogons omvatten aminozuursubstituties, amino en carboxyl eindwijzigingen, en C.sub.6 - acylations C.sub.10. De geëiste samenstellingen bevorderen de afscheiding of de biosynthese van insuline in slecht functionerende bètacellen en zijn daarom nuttig in het behandelen van Type II diabetici