A process for synthesizing L and D-5,5,5,5',5',5'-hexafluoroleucine and
protected analogs is disclosed. These compounds have utility in the
preparation of fluorous peptides and proteins, which display interesting
and unusual properties including strong self-association and an affinity
for lipid bilayers.
Um processo para synthesizing L e D-5,5,5,5',5',5'-hexafluoroleucine e os analogs protegidos são divulgados. Estes compostos têm a utilidade na preparação dos peptides e das proteínas fluorous, que indicam propriedades interessantes e incomuns including o self-association forte e uma afinidade para bilayers do lipid.