Substantially nontoxic manganese complexes of compounds of the formula:
##STR1##
wherein n=0, 1 or 2, R.sub.1 and R.sub.2 are hydrogen or alkyl groups of 1
to 4 carbon atoms, and R.sub.3 and R.sub.4 are hydrogen, alkyl groups of 1
to 4 carbon atoms or halogen, are useful for enhancing magnetic resonance
images of body organs and tissues. Illustrative manganese complexes of
such compounds include dihydrogen
bis(N-[N'-(2,6-Diisopropylphenyl)-carbamoylmethyl-]iminodiaceto)manganese(
II) monohydrate, dihydrogen
bis[N-[N'-(2,6-dimethylphenyl)-carbamoylmethyl]iminodiaceto)-manganese(II)
trihydrate, and dihydrogen
bis(N-[N'-(2,6-dimethylpheny)carbamoylmethyl]iminodiaceto) manganese(II)
dihydrate.
Complexes essentiellement non-toxiques de manganèse des composés de la formule : ## du ## STR1 où n=0, 1 ou 2, R.sub.1 et R.sub.2 sont hydrogène ou les groupes alcoyle de 1 à 4 atomes de carbone, et R.sub.3 et R.sub.4 sont hydrogène, les groupes alcoyle de 1 à 4 atomes de carbone ou l'halogène, soyez utile pour augmenter des images de résonance magnétique des organes et des tissus de corps. Les complexes d'illustration de manganèse de tels composés incluent le monohydrate du dihydrogène bis(N-[N'-(2,6-Diisopropylphenyl)-carbamoylmethyl-]iminodiaceto)manganese(II), le trihydrate du dihydrogène bis[N-[N'-(2,6-dimethylphenyl)-carbamoylmethyl]iminodiaceto)-manganese(II), et le dihydrate de manganese(II) du dihydrogène bis(N-[N'-(2,6-dimethylpheny)carbamoylmethyl]iminodiaceto).
