In the present invention, it is discovered that a compound of formula (I)
has a potent effect for treatment of osteoporosis, arthritis and ruptured
disc:
##STR1##
in which R.sub.1 represents hydrogen atom or alkyl group and R.sub.2
represents hydrogen atom r cinnamoyl group. Therefore, the compound of
formula (I) can be used for prevention and treatment of osteoporosis,
arthritis and ruptured disc. Thus, the present invention provides a
pharmaceutical preparation containing as an effective component a compound
of formula (I) in combination with a pharmaceutically acceptable
auxiliary, diluent, isotonic agent, preservative, lubricant and
solubilizing aid, which is formulated in the form of a pharmaceutically
acceptable preparation and has a potent effect for osteoporosis, arthritis
and ruptured disc.
