There is provided a process for reducing particle size of a drug, the
process comprising (a) a step of dispersing about 10 g or less of the drug
in a suitable volume of a liquid dispersion medium to form a suspension;
(b) a step of bringing together in a vessel grinding media, magnetically
activatable means for stirring and the suspension; (c) a step of
magnetically activating the means for stirring to effect milling of the
suspension to a weight average particle size not greater than about 1
.mu.m; and (d) a step of separating the resulting milled suspension from
the grinding media and the magnetically activatable means for stirring.