The present invention relates to the delivery of compounds for the
treatment of Parkinsons through an inhalation route. Specifically, it
relates to aerosols containing antiparkinsonian drugs that are used in
inhalation therapy. In a composition aspect of the present invention, the
aerosol comprises particles comprising at least 5 percent by weight of an
antiparkinsonian drug. In a method aspect of the present invention, an
antiparkinsonian drug is delivered to a mammal through an inhalation
route. The method comprises: a) heating a composition, wherein the
composition comprises at least 5 percent by weight of an antiparkinsonian
drug to form a vapor; and, b) allowing the vapor to cool, thereby forming
a condensation aerosol comprising particles, which is inhaled by the
mammal. In a kit aspect of the present invention, a kit for delivering an
antiparkinsonian drug through an inhalation route to a mammal is provided
which comprises: a) a composition comprising at least 5 percent by weight
of an antiparkinsonian drug; and, b) a device that forms an
antiparkinsonian drug containing aerosol from the composition, for
inhalation by the mammal.
