Human chemokine .beta.-6 agonist and antagonist polypeptides and DNA
encoding such polypeptides and a procedure for producing such polypeptides
by recombinant techniques are disclosed. The chemokine .beta.-6
antagonists of the present invention may be employed to treat rheumatoid
arthritis, lung inflammation, allergy, asmtha, infectious diseases and to
prevent inflammation and atherosclerosis. The chemokine .beta.-6 agonists
may be employed to myeloprotect patients undergoing chemotherapy.