The present invention relates to methods for identifying one or more
reporter genes for a particular biological pathway of interest. The
reporter genes of this invention are particularly useful for analyzing
the activity of particular biological pathways of interest, and may be
further used in the design of drugs, drug therapies or other biological
agents (e.g., insecticides, herbicides, fungicides, antibiotics, or
antivirals) to target a particular biological pathway. The present
invention also relates to methods for identifying one or more target
genes for a particular biological pathway of interest. Target genes of
the invention are useful as specific targets for drugs which may be
designed to enhance, inhibit, or modulate a particular biological
pathway. Methods to identify genes which modify the function or structure
of a member (e.g., compound or gene product) of a particular biological
pathway are provided.