Reagents which regulate human pyroglutamyl peptidase-like enzyme and
reagents which bind to human pyroglutamyl peptidase-like enzyme gene
products can play a role in preventing, ameliorating, or correcting
dysfunctions or diseases, including, but not limited to, brain and spinal
cord trauma, stroke, and neurodegenerative disorders, such as amyotropic
lateral sclerosis and spinocerebellar degeneration.