Pyrimidinone fused bicyclic metalloproteinase inhibitors

   
   

The present invention relates to fused bicyclic metalloproteinase inhibitors of the formula ##STR1## wherein A, B, X, Y, and R.sup.1 are as defined in the specification, and to pharmaceutical compositions and methods of treating arthritis, inflammation, cancer and other disorders.

De onderhavige uitvinding heeft op gesmolten bicyclische metalloproteinase inhibitors van de formule ## STR1 ## betrekking waarin A, B, X, Y, en R.sup.1 zoals die in de specificatie zijn, en aan farmaceutische samenstellingen en methodes om artritis, ontsteking, kanker en andere wanorde wordt bepaald te behandelen.

 
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