This invention relates to therapeutic and diagnostic methods and
compositions based on Jagged/Notch proteins and nucleic acids, and on the
role of their signaling pathway in endothelial cell migration and/or
differentiation. In addition, this invention provides a substantially
purified Jagged protein, as well as a substantially purified nucleic acid
molecule or segment thereof encoding Jagged protein, or a functionally
equivalent derivative, or allelic or species variant thereof.
