The present invention provides highly dispersible spray-dried powder
compositions, and in particular, inhaleable dry powder compositions for
aerosolized delivery to the lungs. The powders of the invention are
produced by spray drying a 4 .alpha.-helix bundle protein under conditions
which both (i) protect the protein from aggregation and (ii) provide
particles suitable for inhalation (i.e., demonstrating superior aerosol
performance).
A invenção atual fornece composições spray-dried altamente dispersible do pó, e no detalhe, as composições secas inhaleable do pó para aerosolized a entrega aos pulmões. Os pós da invenção são produzidos pela secagem de pulverizador uma proteína do pacote de 4 alpha.-hélices sob as circunstâncias que (i) protege a proteína do aggregation e (ii) fornece as partículas apropriadas para o inhalation (isto é, demonstrando o desempenho superior do aerossol).
