Motilin Homologs

   
   

The present invention is directed to polynucleotides, polypeptides and peptide fragments thereof, and uses thereof for a novel cDNA sequence which has homology to motilin. Tissue distribution of the mRNA for the novel polypeptide is specific to the stomach, small intestine and pancreas. The present invention further includes agonists, antagonists, antibodies, host cells expressing the cDNA encoding the novel motilin homologs and methods for increasing gastric motility using the novel molecules.

A invenção atual é dirigida aos polynucleotides, aos polypeptides e aos fragmentos do peptide disso, e usa-se disso para uma seqüência do DNA da novela que tenha o homology ao motilin. A distribuição do tecido do mRNA para o polypeptide da novela é específica ao estômago, ao intestine pequeno e ao pancreas. A invenção atual mais adicional inclui os agonists, antagonistas, antibodies, pilhas de anfitrião que expressam o DNA que codifica os homologs e os métodos do motilin da novela para aumentar o motility gastric usando as moléculas da novela.

 
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