The present invention is related to polysaccharide esters of N-derivatives
of glutamic acid (N-GA derivatives). These polysaccharidic esters have
antiproliferative activity and are characterized by a low systemic
toxicity. The esters of the invention are used in the prevention and
therapy of diseases caused by cellular hyperproliferation, particularly
psoriasis, tumors, rheumatoid arthritis, or intestinal inflammatory
pathologies.