Modified, hydroxy-substituted aromatic structures having cytoprotective activity

   
   

The present invention is directed to modified, hydroxy-bearing aromatic ring structures having cytoprotective activity. More specifically, in a first embodiment the present invention is directed to phenolic compounds, and in particular steriods (e.g., estrogens), wherein a non-fused polycyclic, hydrophobic substituent is attached to the hydroxy-substituted A-ring thereof. The present invention is further directed to a process for conferring cytoprotection to a population of cells involving the administration of the compound.

A invenção atual é dirigida ao modificado, as estruturas aromatic do anel do hydroxy-rolamento que têm a atividade cytoprotective. Mais especificamente, em uma primeira incorporação a invenção atual é dirigida aos compostos phenolic, e em steriods particulares (por exemplo, estrogens), wherein um substituent polycyclic, hydrophobic non-fundido é unido ao Um-anel hydroxy-substituído disso. A invenção atual é dirigida mais mais a um processo para o cytoprotection conferenciando a uma população das pilhas que envolvem a administração do composto.

 
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