This invention provides isolated nucleic acids encoding mammalian NPFF
receptors, purified mammalian NPFF receptors, vectors comprising nucleic
acid encoding mammalian NPFF receptors, cells comprising such vectors,
antibodies directed to mammalian NPFF receptors, nucleic acid probes
useful for detecting nucleic acid encoding mammalian NPFF receptors,
antisense oligonucleotides complementary to unique sequences of nucleic
acid encoding mammalian NPFF receptors, transgenic, nonhuman animals which
express DNA encoding normal or mutant mammalian NPFF receptors, methods of
isolating mammalian NPFF receptors, methods of treating an abnormality
that is linked to the activity of the mammalian NPFF receptors, as well as
methods of determining binding of compounds to mammalian NPFF receptors,
methods of identifying agonists and antagonists of NPFF receptors, and
agonists and antagonists so identified.
Deze uitvinding verstrekt geïsoleerde nucleic zuren die zoogdiernpff receptoren, gezuiverde zoogdiernpff receptoren, vectoren coderen bestaand uit nucleic zuur dat zoogdiernpff receptoren, cellen codeert bestaand uit dergelijke vectoren, antilichamen die aan zoogdiernpff receptoren, nucleic zuur worden geleid sondes nuttig om nucleic zuur te ontdekken dat zoogdiernpff receptoren, antisense oligonucleotides codeert bijkomend aan unieke opeenvolgingen van nucleic zuur dat zoogdiernpff receptoren, transgenic, nonhuman dieren codeert die het uitdrukkelijke normaal coderen van DNA of mutant zoogdierreceptoren NPFF, methodes om zoogdierreceptoren te isoleren NPFF, methodes om een abnormaliteit die met de activiteit van de zoogdierreceptoren verbonden is NPFF, evenals methodes van het bepalen band van samenstellingen aan zoogdiernpff receptoren, methodes te behandelen om agonists te identificeren f receptors, vectors comprising nucleic acid encoding mammalian NPFF receptors, cells comprising such vectors, antibodies directed to mammalian NPFF receptors, nucleic acid probes useful for detecting nucleic acid encoding mammalian NPFF receptors, antisense oligonucleotides complementary to unique sequences of nucleic acid encoding mammalian NPFF receptors, transgenic, nonhuman animals which express DNA encoding normal or mutant mammalian NPFF receptors, methods of isolating mammalian NPFF receptors, methods of treating an abnormality that is linked to the activity of the mammalian NPFF receptors, as well as methods of determining binding of compounds to mammalian NPFF receptors, methods of identifying agonists and antagonists of NPFF receptors, and agonists and antagonists so identified.
