The present invention relates to substituted imidazo-pyridinones and
imidazo-pyridazinones of general formula 1
wherein Y and R.sup.1 to R.sup.4 are defined as in claim 1, the tautomers,
enantiomers, diastereomers, the mixtures thereof and the salts thereof,
which have valuable pharmacological properties, particularly an
inhibiting effect on the activity of the enzyme dipeptidylpeptidase-IV
(DPP-IV).