A substance including the chemical structures of bicyclo [3.2.1]octan or
the chemical structures of kaurene for the use in a dietary
supplementation or as a constituent in a medicament for the treatment of
non-insulin dependent diabetes mellitus, hypertension and/or the
metabolic syndrome. The unique chemical structures of bicyclo
[3.2.1]octan alone or in a kaurene structure provides the substances,
such as e.g. steviol, isosteviol and stevioside with the capability of
enhancing or potentiating the secretion of insulin in a plasma glucose
dependent manner. The substances including these unique chemical
structures also have the capability of reducing the glucagon
concentration in the blood and/or lowering the blood pressure thereby
providing a self-regulatory treatment system for non-insulin dependent
diabetes mellitus and/or hypertension. In a combination drug which also
comprise a soy protein, and/or soy fiber and/or at least one isoflavone
these substances act synergistically and such combination drugs are
highly useful both prophylacticly or directly in the treatment of e.g.
the metabolic syndrome and obesity and has due to the self-regulatory
effect a widespread applicability as a dietary supplementation.
