The invention relates to a method and to a device for the non-invasive
detection or determination, by Raman spectroscopy, of the concentration of
substances in body fluids. The aim of the invention is to facilitate a
non-invasive in vivo detection of substances in body fluids that allows
for very accurate, reproducible results of analysis while requiring only
little time for measuring which is acceptable for the patient. To this
end, the inventive method and device for carrying out a Raman spectroscopy
of a body fluid in a body tissue (1) records at least two Raman spectrums
under different physical conditions and compares them with each other. The
result of comparison allows detection of the substance one is looking for
and measurement of the concentration of said substance.