This invention provides methods of retentate chromatography for resolving
analytes in a sample. The methods involve adsorbing the analytes to a
substrate under a plurality of different selectivity conditions, and
detecting the analytes retained on the substrate by desorption
spectrometry. The methods are useful in biology and medicine, including
clinical diagnostics and drug discovery.
Esta invenção fornece métodos do chromatography do retentate resolvendo analytes em uma amostra. Os métodos envolvem adsorbing os analytes a uma carcaça sob um plurality de condições diferentes do selectivity, e detectar os analytes retidos na carcaça pelo spectrometry do desorption. Os métodos são úteis na biologia e na medicina, including o diagnóstico e a descoberta clínicos da droga.