The present invention relates generally to methods for stimulating T
cells, and more particularly, to methods to eliminate undesired (e.g.
autoreactive, alloreactive, pathogenic) subpopulations of T cells from a
mixed population of T cells, thereby restoring the normal immune
repertoire of said T cells. The present invention also relates to
compositions of cells, including stimulated T cells having restored
immune repertoire and uses thereof.
