Described is a heterocycle-containing carboxylic acid derivative represented
by the following formula (I):
##STR1##
wherein A represents, for example, a heteroaryl group which contains at least
one nitrogen atom and may have a substituent, B represents, for example, a heteroarylene
group, a CONH group or a group represented by the formula CR6CR7
in which R6 and R7 represents H, a lower alkyl group or the
like, D represents an arylene group, a heteroarylene group or the like, n1 stands
for 0 or 1, M represents, for example, a hydroxyl group or a lower alkoxy group;
or a physiologically acceptable salt thereof. As a retinoic-related compound replacing
retinoic acid, it permits the provision of a preventive and/or therapeutic for
various diseases.