Antitumoral compositions can comprise as therapeutic agent one or several
immunogenic polypeptides, of which at least one is modified so as to have a cell
location different from its native location. Compositions can be based on a recombinant
vector expressing such an immunogenic polypeptide. A recombinant vector comprising
at least the sequences coding for an immunogenic polypeptide originating from a
precocious and/or tardive region of a papillomavirus having a modified location
and a viral particle comprising the vector is also described. Finally, therapeutic
uses of such a composition, such a recombinant vector and such a viral particle
are described.
