Androst-5-ene-3,17 diol is used to
treat or reduce the likelihood of acquiring osteoporosis or menopausal symptoms,
or other diseases affected by estrogen receptor activity, and for conditions which
respond well to DHEA treatment, but where a higher ratio of estrogenic to androgenic
effects is desired. Combination therapies are included, as are kits and pharmaceutical
compositions for providing the active ingredients of claimed methods and combinations.