The present invention provides a compound of formula I
##STR1##
or a pharmaceutically acceptable salt thereof wherein A is a structure i, ii,
iii, or iv
##STR2##
X is CR7; Y is S(O)n, S(NR8),
or S(NR8)(O); Z is NHC(O)R1,
NHC(S)R1, NR-het1, O-het1,
S-het1, or -het2; and n is independently 0, 1, or
2. The compounds of formula I are useful as antimicrobials against a number of
human and veterinary pathogens.