The present invention provides a neurodegenerative disease therapeutic agent
containing as its active ingredient a (15R)-isocarbacycline derivative indicated
by the following formula [I] or a 15-deoxy-isocarbacycline derivative indicated
by the following formula [III]:
##STR1##
(wherein, R1 represents a C1-C6 alkylene
group, and R2 represents a hydrogen atom, a C1-C7,
alkyl group or protective group); or,
##STR2##
(wherein, R1 and R2 are the same as those defined
in formula [I]).
