A novel sorbent suitable for use as a stationary phase in a chromatography column,
the core of which consists of an organic polymer of synthetic or natural origin.
Further, the carrier exhibits a plurality of covalently bonded non-aromatic zwitterionic
groups on its surface. Additionally, the invention also relates to a method for
purifying a particular biological macromolecule, such as a protein or a nucleic
acid, by zwitterionic ion exchange chromatography as well as an ion exchange column
suitable for use in the zwitterionic ion exchange chromatography.