Aminoalcohol derivatives as beta-3 adrenergic receptor agonists

   
   

The present invention relates to a compound formula [I] wherein R1 and R.sup.5 are each independently hydrogen, halogen, lower alkyl, etc., R.sup.2 is hydrogen or an amino protective group, x is bond, -o-o, --O--CH.sub.2--, etc., y is in which Z is bond, --O--(CH.sub.2).sub.m-- (in which m is 1 to 4), etc., R.sup.3 is lower alkanoyl, carboxy, lower alkoxycarbonyl, etc., and R.sup.4 is hydrogen, halogen, hydroxy, phenoxy, lower alkyl, lower alkoxy, etc., and n is 0, 1 or 2, or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence. 1

 
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