Bifunctional molecules and methods for their use are provided. The subject
bifunctional molecules are conjugates of a drug moiety and a pharmacokinetic modulating
moiety, where these two moieties are optionally joined by a linking group. The
bifunctional molecules are further characterized in that they exhibit at least
one modulated pharmacokinetic property upon administration to a host as compared
to a free drug control. The subject bifunctional molecules find use in a variety
of therapeutic applications.
