Polypeptide growth factors, methods of making them, polynucleotides encoding
them, antibodies to them, and methods of using them are disclosed. The polypeptides
comprise an amino acid segment that is at least 90% identical to residues 46-163
of SEQ ID NO:2 or residues 235-345 of SEQ ID NO:2. Multimers of the polypeptides
are also disclosed. The polypeptides, multimeric proteins, and polynucleotides
can be used in the study and regulation of cell and tissue development, as components
of cell culture media, and as diagnostic agents.
