Fluorous tagging compounds and methods of increasing the fluorous nature of compounds

   
   

A method of increasing the fluorous nature of a compound includes the step of reacting the compound with at least one second compound having the formula: 1 wherein Rf is a fluorous group, Rs is a spacer group, d is 1 or 0, m is 1, 2 or 3, Ra is an alkyl group and X is a suitable leaving group. A compound has the formula: 2 wherein Rf is a fluorous group, n is an integer between 0 and 6, m is 1, 2 or 3, Ra is an alkyl group and X is a leaving group.

 
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