In part, the present invention is directed to a system comprising a lapachone
or a prodrug thereof and a polymer, such as a biocompatible and optionally biodegradable
polymer, methods for treatment using the subject polymer compositions, and methods
of making and using the same. In another part, the present invention includes inclusion
complexes of a lapachone or a prodrug thereof and a cyclodextrin, preferably a
-cyclodextrin, such as hydroxypropyl -cyclodextrin, e.g., to improve
the solubility of the lapachone or prodrug thereof.
