Disclosed herein are wound dressings comprising fibrinogen and at least
one procoagulant such as propyl gallate in a therapeutic amount. Also disclosed
are methods of treating wounds, increasing an amount of or rate of coagulation
of blood from a wound, increasing an amount of or rate of clot formation over a
wound, increasing blood platelet counts, activating a coagulation system, increasing
the plasma concentration of fibrinogen, and decreasing the activated partial thromboplastin
time. Also disclosed are an arterial bleeding model and methods of studying arterial bleeding.
