Compositions for the prevention and treatment of obesity, cardiovascular
and coronary artery diseases are provided. The present invention provides
compositions comprising at least one dibenzo-p-dioxine derivatives having
inhibition ability against diacylglycerol acyltransferase (DGAT), and
also provides the use of the compositions as a component of drugs or
dietary supplements intended for the prevention and treatment of obesity,
cardiovascular and coronary artery diseases. Since the compositions of
the invention are nontoxic, allowing their chronic ingestion, easier and
natural control of obesity and related diseases frequently found in obese
people can be realized.