The optically active compound, R(-)-5-[2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-hydroxybenzenesulfonamide
in good optical purity, a metabolite of the 1-adrenergic blocking
agent tamsulosin, and methods for the preparation thereof. Pharmaceutical compositions
including the optically active compound and methods of treatment comprising administration
of an effective -adrenergic antagonistic amount of such compositions to mammals.