The present invention provides a gene Any-RF derived from an insect, having dormancy-control
activity and biological cell-control function; a dormancy-control substance and
a method for preparing the same; as well as a biological cell-control agent, which
comprises, as an effective component, a physiologically active substance having
a biological cell-control function and which never causes any antigen-antibody
reaction in the living body.
The gene encodes for a protein having an amino acid sequence specified as Sequence
No. 1 in SEQUENCE LISTING: Asp-Ile-Leu-Arg-Gly, whose C-terminal is amidated and
having a molecular weight of 570.959. The physiologically active substance comprising
such a gene is a peptide, which can be isolated and purified by adding an acid-methanol
aqueous solution to Antheraea yamamai, triturating the resulting mixture,
centrifuging the same and then treating the resulting supernatant in an HPLC system.
The peptide permits the control of the dormancy of insects and is also useful as
a biological cell-control agent, which comprises, as an effective component, such
a peptide.
