The present invention relates to a preparation method of solvent-free water-dispersible
hydroxypropyl methyl cellulose phthalate nanoparticle, and more particularly, to
a preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose
phthalate nanoparticle, which is environment-friendly and advantageous in disintegration
and dissolution when used as an enteric coating material, which is prepared by
obtaining suitable hydroxypropyl methyl cellulose phthalate (HPMCP) particle through
aqueous emulsification process and regulating content of remaining electrolyte
through ion exchange process.
