The present invention relates to subtilase variants having a reduced tendency
towards inhibition by substances present in eggs, such as trypsin inhibitor type
IV-0. In particular, the variants comprise at least one additional amino acid residue
between positions 42-43, 51-56, 155-161, 187-190, 216-217, 217-218 or 218-219 (in
BASBPN numbering). These subtilase variants are useful exhibiting excellent or
improved wash performance on egg stains when used in e.g. cleaning or detergent
compositions, such as laundry detergent compositions and dishwash composition,
including automatic dishwash compositions. Also, isolated DNA sequences encoding
the variants, expression vectors, host cells, and methods for producing and using
the variants of the invention. Further, cleaning and detergent compositions comprising
the variants are disclosed.