A method in which a mould is coated with a reactive polymer, a liquid curable
composition
is filled into the mould and cured under conditions such that the reactive polymer
becomes covalently bonded to the cured bulk mould material at the interface. The
reactive polymer has zwitterionic groups to confer improved biocompatibility on
the moulded product. The reactive group on the reactive polymer is conveniently
an ethylenically unsaturated group. The curable composition is suitably a radical
polymerisable ethylenically unsaturated monomer mixture or a platinum-curable liquid
silicone composition.