A method of calibrating glucose monitor data includes collecting the glucose
monitor
data over a period of time at predetermined intervals. It also includes obtaining
at least two reference glucose values from a reference source that temporally correspond
with the glucose monitor data obtained at the predetermined intervals. Also included
is calculating the calibration characteristics using the reference glucose values
and the corresponding glucose monitor data to regress the obtained glucose monitor
data. And calibrating the obtained glucose monitor data using the calibration characteristics
is included. In preferred embodiments, the reference source is a blood glucose
meter, and the at least two reference glucose values are obtained from blood tests.
In additional embodiments, the calculation of the calibration characteristics is
obtained using linear regression and in particular embodiments, least squares linear
regression. Alternatively, the calculation of the calibration characteristics is
obtained using non-linear regression.
