A microinfusion device, comprising: (a) a subcutaneously implantable
reservoir configured to contain a drug, the reservoir being mountable
within a burr hole of a skull of a subject; (b) a dose control system
configured to control flow of the drug; and (c) a microcatheter to
deliver the drug from the reservoir to a target location. Another
embodiment provides a microinfusion device, comprising: a subcutaneously
implantable reservoir configured to contain a drug, the implantable
reservoir having at least two outlets. A further embodiment provides a
microinfusion device, comprising: (a) a subcutaneously implantable
reservoir configured to contain a drug, the reservoir being mountable
within a burr hole in a skull of a patient, the reservoir being
ring-shaped; and (b) a microcatheter configured to deliver the drug from
the reservoir to a target location. Yet another embodiment provides a
microinfusion device, comprising: (a) a subcutaneously implantable
reservoir having septations configured to separate different drugs within
the reservoir; and (b) at least one microcatheter configured to deliver
the different drugs from the reservoir to at least one target location.
