The present invention provides a heat exchange reactor, which includes at least
one tube bundle containing a plurality of tubes arranged substantially parallel
to a common longitudinal axis and within an external pressure housing, the bundle
having first and second ends in respective first fluid communication with at least
one first fluid inlet and at least one first fluid outlet, and the external pressure
housing having at least one second fluid inlet and at least one second fluid outlet;
at least one baffle oriented substantially perpendicular to the longitudinal axis
and disposed about the bundle and configured as a manifold to control a flow of
the second fluid; at least one layer of interior thermal insulation disposed between
the bundle and the housing and in fluid communication with the second fluid. Other
embodiments of the present invention include methods of using and methods of making
the heat exchange reactor.